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NDB-TM (HOCl probe) nhbl 87 SMILES: NCCCCCNS(=O)(=O)C1=CC=C(C(=C1)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S([O-])(=O)=O

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Description

87 SMILES: NCCCCCNS(=O)(=O)C1=CC=C(C(=C1)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S([O-])(=O)=O

such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC) and the strain-promoted alkyne-azide cycloaddition (SPAAC)

with a Kd value of 69 nM towards DCAF1 measured by fluorescence polarization

Product Name Pomalidomide-C4-acid Synonyms Pomalidomide-4'-C4-acid CAS Number 2225940-48-5 Related CAS Molecular Formula C18H19N3O6 Molecular Weight 373

Product Name Biotin-PEG4-acid Synonyms CAS Number 721431-18-1 Related CAS Molecular Formula C21H37N3O8S Molecular Weight 491

NDB-TM (HOCl probe) nhbl 87 SMILES: NCCCCCNS(=O)(=O)C1=CC=C(C(=C1)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S([O-])(=O)=ONBD TM is a thiomorpholine based fluorogenic probe for HOCl. NBD TM proved to be the most rapid scavenger of HOCl when compared with boronate and aminophenyl based fluorogenic probes in a study for monitoring the chlorinating activity of Myeloperoxidase (MPO). Its high reactivity towards HOCl makes NBD TM the probe of choice for HTS campaigns based on HOCl detection. Excitation maximum = 500 nm; emission maximum = 550 nm. Product Name NDB TM Synonyms

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