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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP mpeg Product Name Pomalidomide-C3-Br Synonyms Pomalidomide-4'-C3-Br

SKU: 37752023769

4.3
USD445.00 USD492.00

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Description

Product Name Pomalidomide-C3-Br Synonyms Pomalidomide-4'-C3-Br CAS Number n/a Related CAS Molecular Formula C16H16BrN3O4 Molecular Weight 394

Product Name Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C77H95FN12O24 Molecular Weight 1591

VHL-SNAP2-5C is a SNAP PROteolysis TArgeting Chimera (SNAP-PROTAC)

Ready for conjugation to a target protein ligand to form PROTACs containing Thalidomide as cereblon ligand

084 Purity (HPLC) >= 95% Solubility DMSO

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP mpeg Product Name Pomalidomide-C3-Br Synonyms Pomalidomide-4'-C3-BrSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload

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