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Product Name DOTA-PEG4-C2-amine Synonyms CAS Number 2090232-34-9 Related CAS Molecular Formula C26H50N6O11 Molecular Weight 622
providing flexibility in protein labeling and tracking
can be hydrolyzed by intracellular esterases to release the fluorescent fluorescein core
planar structure around the boron-dipyrromethene core imparts exceptional photostability
exhibited longer fluorescence lifetimes than its non-sulfonated counterparts
Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan clip Product Name DOTA-PEG4-C2-amine Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent
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